All the Challenges in The Binding of Isaac Genesis+. There are currently 33.
Challenge list[ | ]
| Name | Conditions | Goal |
|---|---|---|
| 1. Dniwer Emit | Isaac starts in every floor at the boss room
and must arrive the actual start room. Shops and treasure rooms are available. |
???
(Chest) Hard Mode |
| 2. Old School Gamer | Starts with: GB Bug, Ponger, The Gamekid.
The Retro Vision effect acts permanent. No treasure rooms. Shops are available. |
Isaac
(Cathedral) |
| 3. HOLY MERP?! | Starts with: Merp, Child Leash.
Blindfolded (cannot use tears). No treasure rooms. Shops are available. |
Isaac
(Cathedral) |
| 4. Lamby's Shadow | Starts with: Lil' Lamby, Incubus.
Blindfolded (cannot use tears). No treasure rooms. Shops are available. |
Isaac
(Cathedral) |
| 5. A Salty Challenge | Starts with: Salt, Cursed Eye, Dead Eye.
No treasure rooms. Shops are available. |
Isaac
(Cathedral) |
| 6. Brimsnap | Starts with: Brimstone, Soy Milk, Libra.
Shops and treasure rooms are available. |
Isaac
(Cathedral) |
| 7. Isaac's Superpowers | Starts with: Isaac's Tears, SUPER POWERS!, Damage down Pill.
Curse of the Labyrinth acts permanent. Shops and treasure rooms are available. |
Isaac
(Cathedral) |
| 8. The Soulspider | This challenge is done as The Soulless.
Starts with: Book of Revelations. Blindfolded (cannot use tears). Shops and treasure rooms are available. |
Isaac
(Cathedral) |
| 9. STRIKE! | Starts with: Bowling Ball, Habit.
Blindfolded (cannot use tears). No treasure rooms. Shops are available. |
Mom's Heart
(Womb II) |
| 10. Costume Party! | Starts with: White Mask, Missing No.
No treasure rooms. Shops are available. |
Mom's Heart
(Womb II) |
| 11. Lucifer's Paradise | This challenge is done as Lucifer.
Starts with: Lucifer's Wallet, Cursed Contract, Ceremonial Dagger, 1 random Devil Deal item. Additionally, 2 - 3 Devil Deal items spawn at the start. No treasure rooms. Shops are available. |
The Lamb
(Dark Room) |
| 12. Tech Guppy | Starts with: Guppy's Hair Ball, Guppy's Tail, Guppy's Collar, Technology 2, Tech G.
No treasure rooms. Shops are available. |
The Lamb
(Dark Room) |
| 13. Byoux's Power | Starts with: Byoux's Head, Incubus, Mom's Lipstick.
Blindfolded (cannot use tears). No treasure rooms. Shops are available. |
The Lamb
(Dark Room) |
| 14. Goodnight Isaac! | Starts with: Used Pillow, Charm of the Vampire, Placenta.
No treasure rooms. Shops are available. |
The Lamb
(Dark Room) Hard Mode |
| 15. It's time to Draw! | This challenge is done as The Drawn.
Starts with: The Crayon. No treasure rooms. Shops are available. |
The Lamb
(Dark Room) |
| 16. Ninja Practice | ||
| 17. Grant your Wish | ||
| 18. Become the Brain! | ||
| 19. Rainbow Party | ||
| 20. The Devil of Fire | ||
| 21. Hell from Above | ||
| 22. Good or Evil | ||
| 23. Soul Collector | ||
| 24. Technology Expert | ||
| 25. The Weather Man | ||
| 26. Delirious! | ||
| 27. Soy Light | ||
| 28. So Many Options! | ||
| 29. The Broski Challenge | ||
| 30. The Curse of the Cursed | ||
| 31. Slice & Dice | ||
| 32. The Lost God | ||
| 33. The D3 Challenge |
| |||||
